Across International SonoMechanics ISP 3600W Ultrasonic Continuous Liquid Processor

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Power Lab Supply 2SKU: ISP-3600
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Sale price$67,442.62 USD Regular price$68,819.00 USD
Description

Ultrasonic homogenizers, the modern version of "mortar and pestle", they can disrupt tissues and cells through cavitation and ultrasonic waves. Basically, an ultrasonic homogenizer has a tip which very rapidly vibrates, causing bubbles in the surrounding solution to rapidly form and collapse. This creates shear and shock waves which tear apart cells and particles.

Ultrasonic Homogenizers are recommended for homogenization and lysis of laboratory samples that do not require traditional shredding or rotor-stator cutting techniques for processing. Small and large ultrasonic probes are used in a variety of sample volumes to be processed. A solid probe allows for less chance of sample loss and cross-contamination between samples.

Sonication is the act of applying sound energy to agitate particles in a sample, for various purposes. Ultrasonic frequencies (around 20 kHz) are usually used, leading to the process also being known as ultrasonication or ultra-sonication. In the laboratory, it is usually applied using an ultrasonic bath or an ultrasonic probe, colloquially known as a sonifier.

Sonication can be used for the production of nanoparticles, such as nanoemulsions, nanocrystals, liposomes and wax emulsions, as well as for wastewater purification, degassing, extraction of plant oil, extraction of anthocyanins and antioxidants, production of biofuels, crude oil desulphurization, cell disruption, polymer and epoxy processing, adhesive thinning, and many other processes. Sonication is also commonly used in nanotechnology for evenly dispersing nanoparticles in liquids.

Now including a new large-capacity filter ideal when working with larger nanoemulsion volumes. The large-capacity filtration system comprises a stainless-steel housing (one-time purchase) and a replacement cartridge (consumable). Each cartridge is capable of handling significantly larger nanoemulsion volumes than the previous filters and it can be cleaned and reused many times before it needs to be replaced (so not only more efficient but also lower cost of ownership)."

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ISP-3600 in Continuous Mode
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The ISP-3600 industrial-scale ultrasonic liquid processor from Industrial SonoMechanics

The ISP-3600 ultrasonic liquid processor is designed for industrial-scale production. It is suitable for working with liquid volumes above 1 L, with no upper limit.

Features

  • The ISP-3600 ultrasonic liquid processor is most commonly supplied with a 3600 W ultrasonic generator, water-cooled transducer, half-wave booster half-wave Barbell HornĀ® (HBHB), and flow-through reactor chamber (flow cell). Optional items include a half-wave Barbell HornĀ® (HBH) and support stand.
  • The ISP-3600 processor can be used in batch and flow-through configurations (see schematics on the left). Details are available under the SPECIFICATIONS tab.
  • The ISP-3600 processor utilizes patented Barbell HornĀ® Ultrasonic Technology (BHUT), which makes it possible to generate extremely high ultrasonic amplitudes at any scale of operation. With the ISP-3600, any process optimized with our smaller units, the LSP-600 or BSP-1200, can be directly scaled-up to an industrial production environment, while maintaining the same processing conditions and reproducible results. Further scale-up is possible by placing several ISP-3600 processors in parallel and/or in series (see schematics on the left).


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Commercial Production of Water-Soluble botanical extract and plant extract by High-Intensity Ultrasound



How We Scale Up with the Barbell Horn Ultrasonic Technology by Industrial SonoMechanics


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Model ISP-3600
Electrical requirements
220V-240V (15A max.), 50/60Hz
Ultrasonic output 3600 V rms (max.), 20 (+/- 1) kHz, 3600 W (max.)
Additional features Continuous resonant frequency lock, automatic power adjustment,
fine amplitude adjustment and lock (20 - 100%), monitoring of output power
and frequency, optional external control.
Water-cooled piezoelectric transducer
(SWCT-3000)
Output Characteristics: amplitude 24 microns (max.),
frequency 20 (+/- 1) kHz, power 3000 W (max.)
Half-wave booster Barbell Horn
(HBHB, 45 mm tip diameter)
Output characteristics: amplitude 112 microns (max.),
frequency 20 (+/- 1) kHz, power 3000 W (max.)
Flow-through reactor chamber
(flow cell)
: 1" tri-clamp inlet and outlet
Materials of wetted parts
Reactor chamber 304 stainless steel. Food compatible.
Horns (HBHB, HBH) Grade 5 Titanium (Ti6Al4V). Food compatible.
Gaskets Buna-N or Teflon. Food compatible.
O-rings Buna-N. Food compatible.
Noise level
106 - 109 dBa at 2' away. Noise reducing earmuffs or sound enclosure required.
Capacity

1 L - 10 L with HBHB (batch mode)
2 L - unlimited with HBHB or HBH + reactor chamber (flow-through mode)

Productivity rates Productivity rates are highly dependent on the nature of each process and range
from about 5 L/h for challenging tasks (e.g., top-down nanocrystallization of active
pharmaceutical compounds) to over 250 L/h for fast processes
(e.g., degassing, deagglomeration).
4 - 5 times faster processing than with the BSP-1200
20 - 25 times faster processing than with the LSP-600
Optional accessories
Half-wave Barbell Horn (HBH, 45 mm tip diameter, amplitude 94 microns (max.))
Support stand with clamp holders
Noise reduction ear muffs
Heat exchanger
Warranty One year
Download ,
Reading ,

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ISP-3600: Disassembly Procedures, Flow-Through Mode

ISP-3000: Assembly Procedures, Flow-Through Mode

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Making a Translucent Nanoemulsion with ISP-3600, Flow-Through Mode

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Specifications
Specifications

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Ā Model Ā ISP-3600
Ā Electrical requirements
Ā 220V-240V (15A max.), 50/60Hz
Ā Ultrasonic output Ā 3600 V rms (max.), 20 (+/- 1) kHz, 3600 W (max.)
Ā Additional features Ā Continuous resonant frequency lock, automatic power adjustment,
Ā  fine amplitude adjustment and lock (20 - 100%), monitoring of output power
Ā  and frequency, optional external control.
Ā Water-cooled piezoelectric transducer
Ā  (SWCT-3000)
Ā Output Characteristics: amplitude ā€” 24 microns (max.),
Ā  frequencyĀ  20 (+/- 1) kHz, power ā€” 3000 W (max.)
Ā Half-wave booster Barbell HornĀ®
Ā  (HBHB, 45 mm tip diameter)
Ā Output characteristics: amplitude ā€” 112 microns (max.),
Ā  frequency ā€” 20 (+/- 1) kHz, power ā€” 3000 W (max.)
Ā Flow-through reactor chamber
Ā  (flow cell)
Ā Features: 1" tri-clamp inlet and outlet
Ā Materials of wetted parts
Ā Reactor chamber ā€” 304 stainless steel. Food compatible.
Ā Horns (HBHB, HBH) ā€” Grade 5 Titanium (Ti6Al4V). Food compatible.
Ā Gaskets ā€” Buna-N or Teflon. Food compatible.
Ā O-rings ā€” Buna-N. Food compatible.
Ā Noise level
Ā 106 - 109 dBa at 2' away. Noise reducing earmuffs or sound enclosure required.
Ā Capacity

Ā 1 L - 10 L ā€” with HBHB (batch mode)
Ā 2 L - unlimited ā€” with HBHB or HBH + reactor chamber (flow-through mode)

Ā Productivity rates Ā Productivity rates are highly dependent on the nature of each process and range
Ā  from about 5 L/h for challenging tasks (e.g., top-down nanocrystallization of active
Ā  pharmaceutical compounds) to over 250 L/h for fast processes
Ā  (e.g., degassing, deagglomeration).
Ā 4 - 5 times faster processing than with the BSP-1200
Ā 20 - 25 times faster processing than with the LSP-600
Ā Optional accessories
Ā Half-wave Barbell HornĀ® (HBH, 45 mm tip diameter, amplitude ā€” 94 microns (max.))
Ā Support stand with clamp holders
Ā Noise reduction ear muffs
Ā Heat exchanger
Ā Warranty Ā One year
Ā Download Ā , Ā 
Ā Reading Ā , Ā Ā 
Standard Packages
Standard package

Ā Part description

Ā Quantity

Part image

Ā SonoMechanics ISP-3600 system 1 set

Ā Chiller for water-cooled transducer and reactor chamber 1 pc
Ā Peristaltic pump 1 pc Ā 
Ā Half-wave Barbell Horn, output tip diameter - 45mm 1 pc Ā 
Ā  1 pc

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