Solvent in Organic Synthesis:
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- Acetonitrile is often used as a solvent in organic synthesis due to its ability to dissolve a wide range of both polar and nonpolar substances. It's commonly employed in reactions involving electrophilic substitution, nucleophilic substitution, and polymerization.
     High-Performance Liquid Chromatography (HPLC):
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- Acetonitrile is a common solvent in HPLC, where it's used in mobile phases for separating and analyzing compounds, particularly in the pharmaceutical and environmental industries.
     Pharmaceutical Industry:
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- Acetonitrile is used in the production of various pharmaceuticals, particularly in the synthesis of intermediates and active pharmaceutical ingredients (APIs). It helps to purify and isolate compounds in medical formulations.
     Extraction and Purification:
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- Acetonitrile is used in liquid-liquid extraction to separate or purify chemicals, such as when isolating nucleic acids or proteins, and in the extraction of rare earth metals.
     Chemical Manufacturing:
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- It is involved in the production of acetic acid, adiponitrile (for nylon production), and various other chemicals, such as dyes, resins, and plastics.
     Electrochemical Applications:
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- Acetonitrile is used in electrochemical processes due to its high polarity and low viscosity, making it suitable for applications like electroplating and electrochemical cell research.
     Cleaning and Degreasing:
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- In some industrial applications, acetonitrile serves as a cleaning agent, helping to remove grease, oils, and other contaminants from machinery and equipment.
     Gas Chromatography (GC):
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- It can be used as a solvent in GC to help in the analysis and separation of volatile organic compounds.
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Chemical Formula: |
|
Molecular Weight: | 41.05Â g/mol |
CAS Registry Number: | 75-05-8 |
Appearance | Colorless Liquid |
Odor: | Sweet, ethereal |
Density |
0.787 at 68 °F (less dense than water) |
Boiling Point: |  82°C /179 °F |
Solubility in water: | 800 g/L at 25 °C |
GHS Pictograms: | |
GHS Signal Word: | Danger |
GHS Hazard Statements: | H225, H302, H312, H332, H319 |
GHS Precautionary Statements | P210, P233, P240, P241, P243, P261, P264, P270, P271, P280, P301, P212, P330, P303, P361, P353, P304, P340, P312, P305, P351, P338, P337, P313, P363, P370,P378, P403, P235, P501 |
UN Identification Number: | 1648 |
Proper Shipping Name: | Acetonitrile |
Transport Hazard Class: | 3 |
Packing Group: | II |
DOT Placard: |
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